Author of Elémens de chymie théorique (1749), a popular textbook, and the best-selling Dictionnaire de chymie (1766). Lectured on chemistry in cooperation with Antoine Baumé (1757-73) and at the Jardin du roi (1770-83). Particularly interested in applications of chemistry to medicine. Scientific consultant to the Bureau de commerce; participated in investigations of chemical problems in the dyeing, ceramics, and saltpetre industries.
Member of numerous learned societies, including the Académie royale des sciences (1745), the Société royale de médecine, and the American Philosophical Society.
Son of Joseph and Marie-Anne (Caillet) Macquer. Educated at the University of Paris (M.D., 1742). Married in 1748; two daughters.