Friend and correspondent of Franklin on various scientific, literary, and personal matters. Friend and physician of Rousseau. Friend also of Jean-Hyacinthe Magellan and Jan Ingenhousz.
A prolific writer on medical subjects. Received as doctor at the Faculty of Medicine at Paris (1760). Collaborated on the Bibliothèque physico-économique.
Brother of Louis Lebègue de Presle Duportail.